First step-restart your computer. If that doesn't work then go to the Device Manager and uninstall the Icicle. Make sure all sound recording and player programs are NOT active. Now plug in the Icicle and make sure in installs correctly BEFORE you start any other programs. You can verify this in the Device Manager. You may need to restart your computer at this point. Now the device should work and to adjust the settings follow the instructions on the Blue website.
Blue Microphones | Icicle - A Stylish XLR to USB Converter and Preamp