To me the notion is nonsensical, but does the host application in which you record source material have any affect or impartation on its sound? Specifically: during my internship, recording within Nuendo seemed to have a more pleasing raw sound than a.) recording natively in a different application, like Sony Acid Pro or Reaper, or even b.) recording in a different application and importing the files into Nuendo. I discounted this until an engineer I respect recently hinted at this, so I wanted to look into it.