Hey guys, I'm a student working in audio and video post-production. I've looked around but didn't find much on what should be a simple question. Basically, what volume levels are ideal for all my components to minimize hiss and distortion? My setup: iMac, outputting audio via USB to audio interface (M-Audio MobilePre -- ). MobilePre outputting audio via 1/4" TRS cables to powered near-field studio monitors (M-Audio BX5a's -- ). Now there are 4 separate ways to control volume that's being output from my Mac, for a simple example, from iTunes: -iTunes volume control (currently set at around 75%) -Mac's volume control (the traditional system volume [F11/F12] keys become disabled, but I can set an output level through the MobilePre driver installed into System Preferences, currently set at -6dB) -MobilePre's physical knob (the knob I currently and would preferably use to actually turn the volume up and down; turning it halfway up gives me a good amount of loudness) -Volume knob on the back of each studio monitor (each one currently set at just below halfway) So... I've messed around with it a little, but what's the proper way to have things set so I can have just one volume control? I've read conflicting opinions online from people saying you should control audio from the software (eg., iTunes, Logic, Pro Tools), others say not. What volume levels should I ideally set my monitors at, and are they normally set there and rarely if ever adjusted? Thanks for the help.