I recently added an RME 96/52 card to my PC: -ASUS TUSL2-C 1 GHz PIII -Windows 2000 I think I might be having an interupt problem between the RME card and my Layla/24. I originally set up the PC using Opus' optimization document, and set it up as a "standard PC", which I thought does not share PCs. But upon installation of the RME, I find that both the RME and the Layla/24 are sharing IRQ 9. Windows 2000 tells me that there are no conflicts, but I have been getting some strange erratic behavior out of my system since the installation of the RME card...weird audio foghorn sounds periodically during playback that last for about 5-10 seconds...my Waves plug-ins locking up...most times, during shutdown, the system goes through its shutdown routine, but I rarely see the message that tells me it is safe to turn off my PC...maybe once in 10 shutdowns does that message pop up. Other times, it just sits there as a blank screen with a light blue background. Obviously, the easy way to troubleshoot this is to remove one of the devices, and see if the problem goes away, but since the problems are sporatic, and I need both of those devices during most sessions, it is a bit difficult to do. Today, I am doing a vocal overdub session, and I guess I really don't need the Layla today, so I might just try it without, and see what happens. Any other suggestions? Thanks!