Well after toiling with this decision for a while I am going to make a move towards building myself a Cubase/Nuendo rig. I have already spec'd a computer (Dual CPU Dual Opteron - ooooohhh! ). My goal is to build a system that can handle up to 32 I/O's. I need some suggestions on sound cards. Most of the sound cards I have researched can only handle 16 inputs. Are there cards that can handle more? Can a I use more than one 16 input card at a time on my system? Suggestions are welcome, thanks.