I guess they'd be compatible, if that's what you mean. Would I use that gear/program by preference? No.

Cubase will work with any interface so that isn't any issue at all. You could send you master fader from Cubase to the Fast Track Ultra to any pair of it's line outputs to feed a pair of active monitors. I don't like M-Audio much but that is how it would work. Unless I misunderstood your question.