I am not the best for answering, since I have never owned 'high end stuff.'
My experience though has been good for sound quality and a little rough with integration.
Files under "singles" on NoWhereRadio you can hear some of my results using the Q10 with SM57's and Studio Project mics. Everything here is running direct into the Q10 to sonar with little to no plugin effects added. Link:
http://www.nowhereradio.com/artists/discography.php?aid=2999
For another view go search on >> rip rowan q10 << he does a nice job comparing the unit to others you may be familar with.
As far as integration I would call -on phone, talk to live person- someone at Aardvark to talk about the computer you plan to use and verify 100% that there should not be any driver issues.
There are a few very rare situations where this gear can cause headaches - uhh, dual amd processors is one.
I am working now with my new RNP/RNC and an older meek unit to figure which combination of pre's and mics will work best for my situation. Also plan some mic upgrades in near future.
Hope this is some help. Email me directly should you have additional questions or want any other info.
Jim