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More W2K help, please.

Opus 2000, I need your help. I'm trying for the fourth time to get Layla24 and Cubase 5.1 to work over W2K. Clean install, not upgrade on FAT32. Audio disk is formatted with the /z:64 switch.
I have an ASUS CUSL2 mainboard. no onboard audio.
1000GHz PIII
10GB Quantum system disk.
20GB IBM audio disk. Both 7200 RPM ATA100 IDEs on separate channels.