The pres in the OO2R are very clean without being harsh but they offer very little color if that's what you're looking for. I think they're the equivalent to the Focusrite entry level line (in fact I think they're almost identical) I can't speak from experience but I would think they are quite a bit better than the Mackie. I use my Mackie pres only when I have to.- I like my Alesis rack mount mixer's pres better - The Mackies are bright and can give you an edge if that's what you're looking for - but my experience tells me tracks don't seem to "play nicely" when combined using the Mackies.

You should definitely check out the DIGI user conference DUC at their website. Some great informative threads by knowledgeable mods.

Phil

TL Audio 4 X tube pre is nice

TL audio produce a 4 X tube pre setup which would complement the oo2 and not break the bank. It should be around $500.00 US and they sound great for the money.

The Mbox pres are Focusrite Platinum series (entry level).
The 002 and 002R pres are from the same R&D that went into the DigiPRE and are a bit better than the Mbox.
Both are better than the Mackie.

But neither are what I would even call mid-level.

The TL unit would probably add about the same quality level to the 002R, but would give you a different color.