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advise on this mobo/cpu/memory upgrade

After pondering my current setup and doing some research, I am considering upgrading my rig to the following specs. Does anyone have any advice or opinions? Will the retail fan be sufficient, does thermal grease really help? This will go into an Antec PerformancePlus case with 4 cooling fans. 1 front, 1 side and 2 back. I have an Aardvark Q10 soundcard, if that matters.

Am I in the wrong forum? need advice on upgrades!

Here's the story. I have recently been approached by an investor who is willing to fund my studio. Renovations, equipment upgrades, whole new facility, whatever. I just need to com up with a solid plan.
I know enough that I can't get too trigger happy, because if I spend too much it will drive prices up, and business down.