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Dithering in Nuendo Help Please

If I track at 24 bit at 48k, is my sound quality on the final product going to be noticably better? If so, how do I get it to 16bit on the final mix. I have the Wavesuv22 (?) which I think is used to dither from 24 to 16, but I've never used it. Is it hard to get it dithered without getting artifacts such as pops and clicks that I've heard about?