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MOTU 4Pre & Cubase Artist 6, Having Trouble Getting Started

Hi, brand new to the forum and fairly new to home recording. Previously I was an Avid user of Garage Band when I had a Mac, but when my old Powerbook Ti finally became fully obsolete I didn't have the money for another Mac. I ended up with a Lenovo (Idea Pad, I think) laptop and so I'm now using Windows 7.

Universal Audio LA610 Hum issue

Im running a Moog Little Phatty Stage 2 into my LA610 and from the 610 into my Yamaha 01V96 and Im getting a buzz. 2 weeks ago I wasn't...

The exact signal flow including cables is this:
Moog via Mogami TRS to Male XLR cable into the LA610's line input, out of the LA610's line output via Mogami Female XLR cable to TRS into my 01V96.